Point mutation in hemoglobin gene.
In this point mutation, the DNA template strand has an
A
where the wild-type template has a
T
(base-pair substitution).
The mutant mRNA has a
U
instead of an
A
in one codon.
The mutant (sickle-cell) hemoglobin
has a valine
(Val)
instead of a
glutamic acid
(Glu).
