Sensory transduction by a sweetness receptor. Binding of a sugar molecule to a receptor cell initiates a signal transduction pathway involving cyclic AMP and protein kinase A. K^+ channels in the membrane close, and the membrane depolarizes. Voltage-gated calcium Ca^2+ channels open, and Ca^2+ diffuses into the receptor cell. Synaptic vesicles release neurotransmitters, sending signals to the sensory neuron.